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KMID : 1103720150730010001
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Journal of the Korean Society of Radiology
2015 Volume.73 No. 1 p.1 ~ p.10
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Coexistent Coronary Artery Disease or Myocardial Bridging in Patients with Hypertrophic Cardiomyopathy Using Coronary CT Angiography
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Lee Jae-Hwan
Chun Eun-Ju
Kim Yeo-Koon
Yoo Jin-Young
Choi Sang-Il
Choi Dong-Ju
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Abstract
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Purpose
To evaluate the prevalence of coexistent coronary artery disease (CAD) or myocardial bridging (MB) in patients with hypertrophic cardiomyopathy (HCM) using coronary CT angiography (CCTA) and assess the role of CCTA.
Materials and Methods
The prevalence of obstructive CAD (> 50% luminal reduction) and MB (partial and full encasement) were assessed in 150 patients with HCM diagnosed by clinical findings, electrocardiography, and echocardiography of 19588 consecutive patients who underwent CCTA for suspected CAD.
Results
The overall feasibility of coronary artery visualization was 98.9% with CCTA. In patients with HCM, the prevalence of obstructive CAD and MB (14.7% partial and 28.0% full encasement) were 23.3% and 42.7%, respectively. Age, hypertension, family history of premature CAD, Framingham risk score and severe chest pain were associated with CAD, whereas male gender and septal type were associated with MB (all p < 0.05). In comparison to invasive coronary angiography (n = 37), the diagnostic accuracy of CCTA for the detection of CAD and full encasement MB was 89.2% and 86.5%, respectively.
Conclusion
One-quarter of patients with HCM had coexistent obstructive CAD or full encasement MB. CCTA can be a feasible and accurate noninvasive imaging modality for the detection of CAD and MB in patients with HCM.
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KEYWORD
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Hypertrophic Cardiomyopathy, Coronary Artery Disease, Myocardial Bridging, Coronary Computed Tomography Angiography
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